Methadone is one of the strongest opiates. It has a slow onset of action and a long half-life and causes severe respiratory depression which is usually the cause of death.
Some heroin users have overdosed on their 'regular dose', after just a few week's break.
Methadone overdose is a serious medical emergency. In the event of suspected overdose call an ambulance. If the person is losing consciousness lie them on their side in the recovery position so that they will not choke if they vomit.
The term crack refers to the crackling sound that is heard when the mixture is smoked.